| High-fidelity 3D live-cell nanoscopy through data-driven enhanced super-resolution radial fluctuation |
*Romain F Laine*, *Hannah S Heil*, *Simao Coelho*, Jonathon Nixon-Abell, Angélique Jimenez, Tommaso Galgani, Aki Stubb, Gautier Follain, *Siân Culley*, Guillaume Jacquemet, Bassam Hajj, Christophe Leterrier, *Ricardo Henriques*
Published in bioRxiv, April 2022 (see preprint)
Research themes: New Methods, Software
Type: Preprint, Corresponding author
eSRRF (enhanced Super-Resolution Radial Fluctuations) is an extension of the SRRF method developed by the Henriques lab, described in Gustafsson et al. (2016). eSRRF aims at improving the fidelity of SRRF images with respect to the underlying true structure. Below is shown a representative dataset obtained from high-density emitters for which the underlying structure was obtained via DNA-PAINT (SMLM).