Pedro Matos Pereira
Super-Beacons and Beacon-STORM: a new generation of small tunable photoswitching probes and Super-Resolution approaches.
Started January, 2014; ended December, 2018
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I am a cell biologist with extensive scientific knowledge in microbiology, host-pathogen interaction and advanced microscopy approaches. I have over 10 years experience in scientific project design/management, undergraduate and postgraduate student supervision and writing/communication of scientific information to both expert and non-expert audiences. To attest to this I am lead author in several high profile publications with over 1300 citations (Google Scholar: dQvQ0AAAAJ), have supervised multiple Master and PhD students, and have been actively involved in several outreach initiatives (In2Science, ITQB-NOVA open day). I have served in several decision boards in Universidade Nova de Lisboa, University College London and the Francis Crick Institute where I have worked with academic, industrial and political partners to define scientific and institutional vision and impact strategies. Experience that has provided me with a comprehensive view about the scientific landscape. From a research point of view I have made significant contributions in the fields of S. aureus microbiology (e.g. discovering a link between peptidoglycan and wall teichoic acids biosynthesis), host-pathogen interaction (e.g. importance of autolysins for immune evasion, or the role of septins in the recognition of intracellular pathogens) and hardware and software technological innovations for microscopy (e.g. NanoJ-Fluidics and NanoJ-SRRF).
Research themes with our lab
Resources
Collaborators
Buzz Baum
Christophe Leterrier
Eva Frickel
Guillaume Jacquemet
Isabel Llorente-García
Jason Mercer
Jonas Ries
Mike Heilemann
Mariana Pinho
Mark Marsh
Musa Mhlanga
Seamus Holden
Serge Mostowy
Publications with our group (see more on Google Scholar)
| DeepBacs for multi-task bacterial image analysis using open-source deep learning approaches Christoph Spahn, Estibaliz Gómez-de-Mariscal, Romain F Laine, Pedro M Pereira, Lucas von Chamier, Mia Conduit, Mariana G Pinho, Guillaume Jacquemet, Séamus Holden, Mike Heilemann, Ricardo Henriques Published in Nature Communications Biology, July 2022 (see publication) |
| Nanoscale colocalization of NK cell activating and inhibitory receptors controls signal integration David Tomaz, Pedro Matos Pereira, Nadia Guerra, Julian Dyson, Keith Gould, Ricardo Henriques Published in Frontiers in immunology, June 2022 (see publication) |
| Single-molecule super-resolution imaging of T-cell plasma membrane CD4 redistribution upon HIV-1 binding Yue Yuan, Caron Jacobs, Isabel Llorente Garcia, Pedro M Pereira, Scott P.Lawrence, Romain F Laine, Mark Marsh, Ricardo Henriques Published in Viruses, January 2021 (see publication) |
| An Introduction to Live-Cell Super-Resolution Imaging Siân Culley, Pedro M Pereira, Romain F Laine, Ricardo Henriques Published in Imaging from Cells to Animals In Vivo, November 2020 (see publication) |
| Super-Beacons: open-source probes with spontaneous tuneable blinking compatible with live-cell super-resolution microscopy Pedro M Pereira, Nils Gustafsson, Mark Marsh, Musa M Mhlanga, Ricardo Henriques Published in Traffic, March 2020 (see publication or preprint) |
| Between life and death: strategies to reduce phototoxicity in super-resolution microscopy Kalina L Tosheva, Yue Yuan, Pedro Matos Pereira, Siân Culley, Ricardo Henriques Published in Journal of Physics D: Applied Physics, January 2020 (see publication) |
| Nuclear pores as versatile reference standards for quantitative superresolution microscopy Jervis Vermal Thevathasan, Maurice Kahnwald, Konstanty Cieśliński, Philipp Hoess, Sudheer Kumar Peneti, Manuel Reitberger, Daniel Heid, Krishna Chaitanya Kasuba, Sarah Janice Hoerner, Yiming Li, Yu-Le Wu, Markus Mund, Ulf Matti, Pedro Matos Pereira, Ricardo Henriques, Bianca Nijmeijer, Moritz Kueblbeck, Vilma Jimenez Sabinina, Jan Ellenberg, Jonas Ries Published in Nature methods, October 2019 (see publication) |
| Fix your membrane receptor imaging: Actin cytoskeleton and CD4 membrane organization disruption by chemical fixation Pedro M Pereira, David Albrecht, Siân Culley, Caron Jacobs, Mark Marsh, Jason Mercer, Ricardo Henriques Published in Frontiers in immunology, April 2019 (see publication) |
| Automating multimodal microscopy with NanoJ-Fluidics Pedro Almada, Pedro M Pereira, Siân Culley, Ghislaine Caillol, Fanny Boroni-Rueda, Christina L Dix, Guillaume Charras, Buzz Baum, Romain F Laine, Christophe Leterrier, Ricardo Henriques Published in Nature communications, March 2019 (see publication) |
| NanoJ: a high-performance open-source super-resolution microscopy toolbox Romain F Laine, Kalina L Tosheva, Nils Gustafsson, Robert DM Gray, Pedro Almada, David Albrecht, Gabriel T Risa, Fredrik Hurtig, Ann-Christin Lindås, Buzz Baum, Jason Mercer, Christophe Leterrier, Pedro M Pereira, Siân Culley, Ricardo Henriques Published in Journal of Physics D: Applied Physics, February 2019 (see publication) |
| TMEM16F activation by Ca 2+ triggers plasma membrane expansion and directs PD-1 trafficking Christopher Bricogne, Michael Fine, Pedro M Pereira, Julia Sung, Maha Tijani, Youxue Wang, Ricardo Henriques, Mary K Collins, Donald W Hilgemann Published in Scientific reports, January 2019 (see publication) |
| Septins recognize and entrap dividing bacterial cells for delivery to lysosomes Sina Krokowski, Damián Lobato-Márquez, Arnaud Chastanet, Pedro Matos Pereira, Dimitrios Angelis, Dieter Galea, Gerald Larrouy-Maumus, Ricardo Henriques, Elias T Spiliotis, Rut Carballido-López, Serge Mostowy Published in Cell host & microbe, December 2018 (see publication) |
| Nanoscale colocalization of NK cell activating and inhibitory receptors controls signal integration David Tomaz, Pedro Matos Pereira, Nadia Guerra, Julian Dyson, Ricardo Henriques, Keith Gould Published in bioRxiv, August 2018 (see preprint) |
| SRRF: Universal live-cell super-resolution microscopy Siân Culley, Kalina L Tosheva, Pedro Matos Pereira, Ricardo Henriques Published in The international journal of biochemistry & cell biology, August 2018 (see publication) |
| Quantitative mapping and minimization of super-resolution optical imaging artifacts Siân Culley, David Albrecht, Caron Jacobs, Pedro Matos Pereira, Christophe Leterrier, Jason Mercer, Ricardo Henriques Published in Nature methods, April 2018 (see publication) |
| K63-linked ubiquitination targets Toxoplasma gondii for endo-lysosomal destruction in IFNγ-stimulated human cells Barbara Clough, Joseph D Wright, Pedro M Pereira, Elizabeth M Hirst, Ashleigh C Johnston, Ricardo Henriques, Eva-Maria Frickel Published in PLoS pathogens, November 2016 (see publication) |
| Fast live-cell conventional fluorophore nanoscopy with ImageJ through super-resolution radial fluctuations Nils Gustafsson, Siân Culley, George Ashdown, Dylan M Owen, Pedro Matos Pereira, Ricardo Henriques Published in Nature communications, August 2016 (see publication) |
| VirusMapper: open-source nanoscale mapping of viral architecture through super-resolution microscopy Robert DM Gray, Corina Beerli, Pedro Matos Pereira, Kathrin Maria Scherer, Jerzy Samolej, Christopher Karl Ernst Bleck, Jason Mercer, Ricardo Henriques Published in Scientific reports, July 2016 (see publication) |
| High-content 3D multicolor super-resolution localization microscopy Pedro M Pereira, Pedro Almada, Ricardo Henriques Published in Methods in cell biology, January 2015 (see publication) |