Cell Signalling

Team members:

Group Leader at IGC and Honorary Professor at UCL

Šarić Lab, University College London, UK

Hoogenboom Lab, University College London, UK

Human immunobiology and Pathogenesis Lab, CEDOC, Nova Medical School, Portugal

Llorente-García Lab, University College London, UK

Viral Cell Biology Lab, University of Birmingham, UK

Cellular Mechanisms of Virus Entry and Assembly Lab, University College London, UK

Gene Expression & Biophysics Lab, University of Cape Town, South Africa

Application of Super-Resolution and Advanced Quantitative Microscopy to the Spatio-Temporal Analysis of Influenza Virus Replication
Emma Touizer, Christian Sieben, *Ricardo Henriques*, Mark Marsh, *Romain F. Laine*
Published in Viruses, January 2021 (see publication)
Research themes: Cell Signalling, Host-Pathogen Interactions, Microbiology, Structural Biology
Type: Review

Single-molecule super-resolution imaging of T-cell plasma membrane CD4 redistribution upon HIV-1 binding
*Yue Yuan*, *Caron Jacobs*, Isabel Llorente Garcia, *Pedro M Pereira*, Scott P.Lawrence, *Romain F Laine*, Mark Marsh, *Ricardo Henriques*
Published in Viruses, January 2021 (see publication)
Research themes: Cell Signalling, Host-Pathogen Interactions, Microbiology, Structural Biology
Type: Paper, Corresponding author

Fix your membrane receptor imaging: Actin cytoskeleton and CD4 membrane organization disruption by chemical fixation
*Pedro M Pereira*, *David Albrecht*, *Siân Culley*, *Caron Jacobs*, Mark Marsh, Jason Mercer, *Ricardo Henriques*
Published in Frontiers in immunology, April 2019 (see publication)
Research themes: Cell Signalling, New Methods
Type: Paper, Corresponding author

TMEM16F activation by Ca 2+ triggers plasma membrane expansion and directs PD-1 trafficking
Christopher Bricogne, Michael Fine, *Pedro M Pereira*, Julia Sung, Maha Tijani, Youxue Wang, *Ricardo Henriques*, Mary K Collins, Donald W Hilgemann
Published in Scientific reports, January 2019 (see publication)
Research themes: Cell Signalling
Type: Paper

Nanoscale colocalization of NK cell activating and inhibitory receptors controls signal integration
David Tomaz, *Pedro Matos Pereira*, Nadia Guerra, Julian Dyson, *Ricardo Henriques*, Keith Gould
Published in bioRxiv, August 2018 (see preprint)
Research themes: Cell Signalling
Type: Preprint

Super-resolution microscopy reveals a preformed NEMO lattice structure that is collapsed in incontinentia pigmenti
Janine Scholefield, *Ricardo Henriques*, Anca F Savulescu, Elisabeth Fontan, Alix Boucharlat, Emmanuel Laplantine, Asma Smahi, Alain Israël, Fabrice Agou, Musa M Mhlanga
Published in Nature communications, September 2016 (see publication)
Research themes: Cell Signalling, Structural Biology
Type: Paper, Co-first author

TNF and IL-1 exhibit distinct ubiquitin requirements for inducing NEMO–IKK supramolecular structures
Nadine Tarantino, Jean-Yves Tinevez, Elizabeth Faris Crowell, Bertrand Boisson, *Ricardo Henriques*, Musa Mhlanga, Fabrice Agou, Alain Israël, Emmanuel Laplantine
Published in Journal of Cell Biology, January 2014 (see publication)
Research themes: Cell Signalling
Type: Paper

Regulated vesicle fusion generates signaling nanoterritories that control T cell activation at the immunological synapse
Helena Soares, *Ricardo Henriques*, Martin Sachse, Leandro Ventimiglia, Miguel A Alonso, Christophe Zimmer, Maria-Isabel Thoulouze, Andrés Alcover
Published in Journal of Experimental Medicine, October 2013 (see publication)
Research themes: Cell Signalling
Type: Paper